Sr. Scientist, Computational Biology

Job Description

Altos Labs is seeking a highly motivated Computational Biology Scientist to contribute to its hybrid AI initiative. The successful candidate will work in a multi-disciplinary research environment, assisting investigators in algorithm development and implementation across the software development life cycle. This role involves working with quantitative “big data” and building predictive models to develop novel theories, with the ultimate goal of improving human lives through better-informed treatments.

Responsibilities:

• Contribute to modeling, simulation, and analysis of mechanistic or data-driven models of biological processes through software development.
• Explore and develop ML algorithms to solve complex problems and draw conclusions.
• Design and implement pipelines to mechanistically model cellular processes from model instantiation to simulation, calibration, and analysis.
• Collaborate with other scientists to characterize model behaviors, predictions, refinements, and accelerate the biological knowledge discovery.
• Develop research programs on partial cellular reprogramming.
• Work at the interface between mathematical and computational models, and AI methods.
• Collaborate with both experimental and computational scientists across Altos.
• Influence best practices in areas such as Bayesian optimization, causal inference and more.
• Maintain documentation and contribute to software releases.

Requirements:

• PhD in Biology, Computational Biology, Computer Science, or closely related field.
• Relevant industry and/or academic experience.
• Expertise and a track record of using methods from artificial intelligence for biological design.
• Record of applications of dynamical systems to problems of synthetic biology.
• Record of applications of data driven modeling methods and AI to synthetic biology.
• Experience working with mechanistic models (PDE/ODE, SDE, dynamical systems).
• Experience working with state of the art ML tools (transformers, GNN, etc.)
• Working knowledge of cell biology.
• Experience with Python, C, R or related scientific computing languages.

Altos Labs offers:

• A culture of collaboration and scientific excellence.
• Inclusion and belonging to inspire innovation.