Principal Central Monitor

Job Description

Precision Medicine Group is seeking a Principal Central Monitor to strategically lead data integrity, patient safety, and operational excellence across clinical development programs. This role involves shaping and executing enterprise-wide RBQM strategies, leading complex risk assessments, and defining key risk indicators (KRIs). The Principal Central Monitor will oversee the design and implementation of centralized statistical monitoring frameworks and lead RBQM governance forums. They will also ensure proactive risk detection and mitigation across portfolios, providing strategic oversight for high-impact studies and therapeutic areas.Role involves:

• Leading the development of RBQM plans.
• Conducting thorough risk assessments for clinical studies.
• Designing and overseeing the implementation of advanced centralized statistical monitoring frameworks.
• Leading monthly RBQM meetings.
• Ensuring high standards of data quality and integrity.
• Preparing detailed reports and presentations on monitoring activities.
• Overseeing operational study metrics.
• Mentoring junior colleagues.
• Leading discussions with Sponsors around risk management and proactive data cleaning.

Requirements:

• Bachelor’s Degree in a relevant field.
• Minimum 8 years experience in clinical monitoring or clinical trial management.
• Working knowledge of ICH GCP guidelines.
• Effective communication skills.
• Excellent organizational and time management skills.
• Strong understanding of RBQM principles and methodologies.
• Proficiency in statistical analysis and data monitoring tools.
• Detail-oriented with strong analytical and problem-solving skills.
• Experience with integrated risk planning & management.
• Ability to mentor junior team members.

Role offers:

• Opportunity to lead and shape RBQM strategies.
• Mentoring and leadership opportunities.
• Contribution to global process innovation.