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Job Description
Xaira Therapeutics, an innovative biotech startup, is seeking a Senior Scientist to advance molecular screening platforms and data-driven discovery methodologies in antibody discovery workflows. The Senior Scientist will play a key role in driving innovation across multidisciplinary teams and ensuring high throughput and efficiency in discovery biology efforts.

Responsibilities:
  • Build and lead HT protein library benchmarking studies for antibody discovery.
  • Evaluate and validate new library designs through routine library benchmarking.
  • Design, qualify, and productionize high-throughput molecular product screening technologies.
  • Establish workflows for hit selection, isolation, and purification.
  • Coordinate the synthesis, build and validation of design libraries.
  • Partner with bioinformatics, bioanalysts, and machine learning teams.
  • Recruit, train, and mentor team members.
  • Utilize cutting-edge methodologies to generate high-throughput data.

Requirements:
  • Ph.D. in Molecular Biology, Microbiology, Synthetic Biology or related field.
  • 5-8+ years of industry experience in large molecule hit identification.
  • Experience building and screening antibody yeast and phage display libraries.
  • Strong background in large-scale molecular biology techniques.
  • Familiarity with bioinformatics and machine learning.
  • Excellent organizational and project management skills.
  • Strong leadership and mentorship experience.
  • Proven ability to collaborate effectively across multidisciplinary teams.
  • Experience establishing and managing lab infrastructure from scratch.
  • Expertise in developing workflows for hit validation, isolation, and purification.
  • Prior work in metagenomics and protein engineering pipelines.

Xaira Therapeutics Offers:
  • Competitive compensation and benefits package.
  • Bonus and equity.
  • Open, flexible, and friendly work environment.
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Xaira Therapeutics

Xaira Therapeutics is a biotech startup pioneering AI-driven drug discovery. Headquartered in the San Francisco Bay Area, Seattle, and London, Xaira develops generative AI models for protein and antibody therapeutics, targeting historically challenging molecular targets. The company also creates foundation models for biology and disease to improve target identification and patient stratification, with the aim of accelerating the development of novel therapies and improving success rates in drug development.

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