Job Description
Precision Medicine Group is seeking a Senior Research Associate to perform routine immunological, molecular, and cellular assay-based services for government and commercial clients. The Senior Research Associate will reliably perform services such as cell culture and bioassays, including luciferase-based neutralizing antibody assays. They will also be responsible for critical reagent production, human primary cell isolations, cultivation, ELISA, ELISpot assays, and other related cell-based assays. Duties include recording and reporting results, preparing samples and solutions, and maintaining equipment. The role involves inventorying, processing, and cryopreserving biological samples.
Responsibilities: - Maintains cell cultures, harvests, and cryopreserves cells per SOPs
- Conducts immunological assays including NAb assay, as well as ELISA, ELISpot, MSD, etc.
- Independently plans and conducts bioassays various scales and for different customers
- Performs QC analyses (luciferase-based assays) to ensure that results meet specifications.
- Monitors assays and trouble shoots, as appropriate
- Performs research and development activities to support new product development.
- Performs new assay development as needed
- Assists Scientists to modify and re-optimize current assays or procedures to address changing technologies or the introduction of new assays
- Completes all paperwork completely and accurately for QA/QC and GLP purposes using Good Documentation Practices (GDP) and updates computer tracking systems, as required
- Operates equipment such as spectrophotometer, MSD plate reader and performs processes in accordance with SOPs
- Assists in the training of new and existing laboratory staff in accordance with SOPs.
- Drafts and/or edits SOPs as needed, to include validation documents for new equipment, new documents and other quality documents
- Evaluates opportunities for revision of SOPs and makes necessary recommendations to improve efficiency and quality
- Organizes data prior to submission.
- Ensures lab maintenance activities and equipment calibration is performed according to schedule.
- Plans for raw material requirements, maintenance of appropriate inventory of reagents and submission of purchase orders
- Maintains a clean and safe lab environment
- Carry out other duties/projects as assigned
Requirements: - Bachelor’s Degree (Biology, Chemistry, Life Sciences or other related discipline)
- 4 years’ relevant laboratory experience or equivalent combination of education and experience
- Previous experience with cell-based assays such as NAb, ELISpots or others
- Requires good attention to detail, excellent documentation skills and willingness to work well in a group environment
- Ability to interact and function in a highly productive work environment
- Ability to work independently
- Must be proficient using Microsoft office, specifically with Excel
- Ability to lift and carry between 1-15 lbs.; Ability to lift up to 50 lbs. overhead with assistance; frequently required to sit, grasp, and use right/left finger dexterity; May be exposed to a cold freezer environment (Freezer temperatures range between -20ºC -196ºC)
- Must be able to read, write, speak fluently and comprehend the English language
The role offers: - Discretionary annual bonus
- Health insurance
- Retirement savings benefits
- Life insurance and disability benefits
- Parental leave
- Paid time off for sick leave and vacation